Francesco Finamore

People, Technical Staff



Since its first definition introduced in 1994, the term “proteome” has gained increasing importance in biological science. The complex and dynamic nature of the proteome, many fold larger than the genome due to the wide degree of protein isoforms, post-translational modifications and processing that nearly all proteins undergo, made of proteomics one of the most challenging disciplines in natural sciences.

The development of high-throughput techniques for protein sample preparation, peptide separation through chromatography, data acquisition through tandem mass spectrometry (MS) approaches and bioinformatics analysis is fundamental to unravel the diverse properties of proteomes from tissues, cells and bio fluids. In this scenario, mass spectrometry plays a crucial role in enabling the analysis of proteomes allowing the qualitative /quantitative characterization of protein dynamics from samples with high complexity.

Francesco Finamore obtained his Master Degree in Molecular and Cellular Biotechnologies from the University of Rome “La Sapienza”, Italy, and a PhD in Structural Biology and Bioinformatics from the University of Geneva, Switzerland. In this context, he focused his attention in studying the mechanisms underlying the mutual competition between protein glycation and aspirin-mediated acetylation in hyperglycemia and type 2 diabetes mellitus through classical shotgun proteomics, targeted proteomics and structural biology MS-based methods.

Following two post-doctoral researcher positions at the Laboratory of Molecular and Chemical Biology of Neurodegeneration at the Ecole Polytechnique Fédérale de Lausanne (EPFL, Lausanne, Switzerland) and at the National Research Council of Italy (CNR, Pisa, Italy), he joined the Proteomics and Metabolomics laboratory of FPS as technologist with the aim of developing proteomics, MS and data analysis approaches for technical services and project collaborations.