Martina Modena

People, PhD Student

PhD Student
Laboratory of Genomics and Transcriptomics


+39 050 8753553

Sudden cardiac death (SCD) is defined as a sudden unexpected death in an otherwise healthy person within 1 hour after the onset of symptoms or, when unwitnessed, within 24 hours after the person was last seen in good health. The teenage years and the first adult age are the life periods when SCD most often occurs, with an estimated incidence ranging from 1 to 10 cases/100,000 people/year from 1 to 40 years of life. Among known predisposing factors to SCD there are cardiomyopathies, channelopathies, congenital cardiac defects, myocarditis, chest trauma, drugs or substances intake. Furthermore, strategies for molecular autopsy have not been standardized yet, largely because of our very limited knowledge of the molecular bases of SCD in the young.

Martina Modena’s project aims to expand knowledge of the molecular bases of SCD in the young through the use of cutting-edge genomics and transcriptomics techniques. The ultimate goals are to define the optimal approach to molecular autopsy in SCD cases, and to molecular screening in family members of subjects at risk for SCD. This project discloses many opportunities for translational and clinical research, beyond its clear social and medical impact.

She received her Master’s degree in Biology Applied to Biomedicine (neurobiological curriculum) at the University of Pisa.

Martina Modena is a student of the PhD program in Translational Medicine of the Scuola Sant’Anna of Pisa and spends most of her research time at the FPS, under the supervision of Chiara Maria Mazzanti.